MICRO AND NANOPLASTICS IN TERRESTRIAL MAMMALS: CURRENT KNOWLEDGE AND RESEARCH GAPS

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• Available online in Detritus - In Press
• Pages

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Abstract

Micro and nano plastics (MNPs), originating from environmental pollution, consumer products and industrial processes, are being detected increasingly across numerous ecosystems and food chains. Their pervasive nature elevates the possibility of human and animal exposure through ingestion, inhalation and dermal contact, underscoring the need for scientific investigations into their presence and effects on “One Health”. With a view to consolidating the current state of knowledge, identifying similarity between humans and animals, research gaps and paving the way for evaluating the potential toxicological and health implications of these particles, a crucial systematic literature review has been conducted to study the detection of MNPs in specific mammalian (human and animal) tissues, whilst also examining experimental models assessing their toxicological effects. By synthesizing findings across biomedical and environmental research, the review elucidates the pathways through which these particles enter and accumulate in the body. Furthermore, it highlights the potential health risks posed by chronic exposure, including inflammatory responses, oxidative stress, and tissue damage. However, the current evidence remains insufficient to establish a quantitative balance across exposure routes and body tissues due to the lack of harmonized exposure data, heterogeneity in methodologies, inconsistent reporting, and lack of biological/clearance data. Recognition of this constraint is crucial to a more accurate contextualization of current findings, which is key for the purpose of shaping public health policies and regulatory frameworks to mitigate exposure to microplastics. Given the interdisciplinary nature of the topic, the review bridges diverse fields to create a robust foundation for future research

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Keywords

• Micro and nano plastic, Waste Management, Environmental pollution, One Health, Terrestrial mammals

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Editorial History

• Received: 28 Aug 2025
• Revised: 08 Nov 2025
• Accepted: 27 Nov 2025
• Available online: 11 Dec 2025

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References

Abbasi S, Turner A (2021) Human exposure to microplastics: A study in Iran. Journal of Hazardous Materials, 403, 123799.
DOI 10.1016/j.jhazmat.2020.123799

Adhikari, K., Pearce, C. I., Sanguinet, K. A., Bary, A. I., Chowdhury, I., Eggleston, I., Xing, B., & Flury, M. (2024). Accumulation of microplastics in soil after long-term application of biosolids and atmospheric deposition. Science of The Total Environment, 912, 168883.
DOI 10.1016/j.scitotenv.2023.168883

Alencastre-Santos A, Silva D, Ribeiro-Brasil D, Correia L, Garcia M, Vieira T (2024) Microplastic Contamination in Amazon Vampire Bats (Desmodontinae: Phyllostomidae). Diversity, 17(1), 31.
DOI 10.3390/d17010031

Allen S, Allen D, Phoenix VR, Le Roux G, Durántez Jiménez P, Simonneau A, Binet S, Galop D (2019) Atmospheric transport and deposition of microplastics in a remote mountain catchment. Nature Geoscience, 12(5), 339–344.
DOI 10.1038/s41561-019-0335-5

Altuğ H, Erdoğan Ş (2022) Wastewater Treatment Plants as a Point Source of Plastic Pollution. Water, Air, & Soil Pollution, 233(12), 488.
DOI 10.1007/s11270-022-05962-6

Amato-Lourenço LF, Carvalho-Oliveira R, Júnio GR, dos Santos Galvão L, Ando RA, Mauad T (2021) Presence of airborne microplastics in human lung tissue. Journal of Hazardous Materials, 416, 126124.
DOI 10.1016/j.jhazmat.2021.126124

Amereh F, Amjadi N, Mohseni-Bandpe A, Isazadeh S, Mehrabi Y, Eslami A, Naeiji Z, Rafiee M (2022) Placental plastics in young women from general population correlate with reduced foetal growth in IUGR pregnancies. Environmental Pollution, 314, 120174.
DOI 10.1016/j.envpol.2022.120174

Aminah, I.S., Ikejima, K. Potential sources of microplastic contamination in laboratory analysis and a protocol for minimising contamination. Environ Monit Assess 195, 808 (2023).
DOI 10.1007/s10661-023-11410-7

Baeza-Martínez C, Olmos S, González-Pleiter M, López-Castellanos J, García-Pachón E, Masiá-Canuto M, Hernández-Blasco L. Bayo J (2022) First evidence of microplastics isolated in European citizens’ lower airway. Journal of Hazardous Materials, 438, 129439.
DOI 10.1016/j.jhazmat.2022.129439

Bahrani F, Mohammadi A, Dobaradaran S, De-la-Torre GE, Arfaeinia H, Ramavandi B, Saeedi R, Tekle-Röttering A (2024) Occurrence of microplastics in edible tissues of livestock (cow and sheep). Environmental Science and Pollution Research, 31(14), 22145–22157.
DOI 10.1007/s11356-024-32424-9

Bandini F (2022) The treatment of the organic fraction of municipal solid waste (OFMSW) as a possible source of micro- and nano-plastics and bioplastics in agroecosystems: A review. Chem. Biol. Technol. Agric. 9(4).
DOI 10.1186/s40538-021-00269-w

Beaurepaire M, Dris R, Gasperi J, Tassin B (2021) Microplastics in the atmospheric compartment: A comprehensive review on methods, results on their occurrence and determining factors. Current Opinion in Food Science, 41, 159–168.
DOI 10.1016/j.cofs.2021.04.010

Björvang R D, Mamsen L S (2022) Sexually Dimorphic Accumulation of Persistent Organic Pollutants in Fetuses. Frontiers in Toxicology, 4.
DOI 10.3389/ftox.2022.909307

Bochicchio D, Cantu L, Cadario M , Palchetti, L, Natali F, Monticelli L, Rossi G, Del Favero E (2022) Polystyrene perturbs the structure, dynamics, and mechanical properties of DPPC membranes: An experimental and computational study. Journal of Colloid and Interface Science, 605, 110–119.
DOI 10.1016/j.jcis.2021.07.069

Chen C, Liu F, Quan S, Chen L, Shen A, Jiao A, Qi H, Yu G (2023) Microplastics in the Bronchoalveolar Lavage Fluid of Chinese Children: Associations with Age, City Development, and Disease Features. Environmental Science & Technology, 57(34), 12594–12601.
DOI 10.1021/acs.est.3c01771

Çobanoğlu , Belivermiş, M, Sıkdokur E, Kılıç Ö, Çayır A (2021) Genotoxic and cytotoxic effects of polyethylene microplastics on human peripheral blood lymphocytes. Chemosphere, 272, 129805.
DOI 10.1016/j.chemosphere.2021.129805

Cole M, Lindeque P, Fileman , Halsband C, Goodhead R, Moger J, & Galloway T S (2013) Microplastic Ingestion by Zooplankton. Environmental Science & Technology, 47(12), 6646–6655.
DOI 10.1021/es400663f

Colombini G, Rumpel C, Houot S, Biron P, Dignac MF (2022) A long-term field experiment confirms the necessity of improving biowaste sorting to decrease coarse microplastic inputs in compost amended soils. Environmental Pollution, 315, 120369.
DOI 10.1016/j.envpol.2022.120369

Commission Regulation (EU) 2023/… of 25 September 2023 amending Annex XVII to Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) as regards synthetic polymer microparticles. (n.d.) https://eur-lex.europa.eu/eli/reg/2023/2055/oj/eng. Acceessed 23 May 2025

Corradini, F., Meza, P., Eguiluz, R., Casado, F., Huerta-Lwanga, E., & Geissen, V. (2019). Evidence of microplastic accumulation in agricultural soils from sewage sludge disposal. Science of The Total Environment, 671, 411–420.
DOI 10.1016/j.scitotenv.2019.03.368

Correia LL, Ribeiro-Brasil DRG, Garcia MG, Silva DDME, Alencastre-Santos AB, Vieira TB (2024) The First Record of Ingestion and Inhalation of Micro- and Mesoplastics by Neotropical Bats from the Brazilian Amazon. Acta Chiropterologica, 25(2).
DOI 10.3161/15081109ACC2023.25.2.015

Cox KD, Covernton GA, Davie HL, Dower JF, Juanes F, Dudas SE (2019) Human Consumption of Microplastics. Environmental Science & Technology, 53(12), 7068–7074.
DOI 10.1021/acs.est.9b01517

Dehority BA (2002) Gastrointestinal Tracts of Herbivores, Particularly the Ruminant: Anatomy, Physiology and Microbial Digestion of Plants. Journal of Applied Animal Research, 21(2), 145–160.
DOI 10.1080/09712119.2002.9706367

Demirelli E, Tepe Y, Oğuz U, Aydın H, Kodat M, Tok D S, Sönmez MG, Öğreden E (2024) The first reported values of microplastics in prostate. BMC Urology, 24(1), 106.
DOI 10.1186/s12894-024-01495-8

Dominelli P, Ripoll JG, Cross TJ, Baker SE, Wiggins CC, Welch BT, Joyner MJ (2018) Sex differences in large conducting airway anatomy. Journal of Applied Physiology, 125(3), 960–965.
DOI 10.1152/japplphysiol.00440.2018

Du T, Yu X, Shao S, Li T, Xu S, Wu L (2023) Aging of Nanoplastics Significantly Affects Protein Corona Composition Thus Enhancing Macrophage Uptake. Environmental Science & Technology, 57(8), 3206–3217.
DOI 10.1021/acs.est.2c05772

Dufreneix F, Faverdin P, Peyraud J (2019) Influence of particle size and density on mean retention time in the rumen of dairy cows. Journal of Dairy Science, 102(4), 3010–3022.
DOI 10.3168/jds.2018-15926

Edo C, Fernández-Piñas F, Rosal R (2022) Microplastics identification and quantification in the composted Organic Fraction of Municipal Solid Waste. Science of The Total Environment, 813, 151902.
DOI 10.1016/j.scitotenv.2021.151902

Fulop T, Larbi A, Dupuis G, Le Page A, Frost E, Cohen A, Witkowski JM, Franceschi C (2018) Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes? Frontiers in Immunology, 8, 1960.
DOI 10.3389/fimmu.2017.01960

Gade M, Comfort N, Re DB (2021) Sex-Specific Neurotoxic Effects of Heavy Metal Pollutants: Epidemiological, Experimental Evidence and Candidate Mechanisms. Environmental Research, 201, 111558.
DOI 10.1016/j.envres.2021.111558

Garcia MA, Liu R, Nihart A, El Hayek E, Castillo E, Barrozo ER, Suter MA, Bleske B, Scott J, Forsythe K, Gonzalez-Estrella J, Aagaard KM, Campen MJ (2024) Quantitation and identification of microplastics accumulation in human placental specimens using pyrolysis gas chromatography mass spectrometry. Toxicological Sciences, 199(1), 81–88.
DOI 10.1093/toxsci/kfae021

Gigault J, Halle AT, Baudrimont M, Pascal PY, Gauffre F, Phi T, El Hadri H, Grassl B, Reynaud S (2018) Current opinion: What is a nanoplastic? Environmental Pollution, 235, 1030–1034.
DOI 10.1016/j.envpol.2018.01.024

Gong X, Tian L, Wang P, Wang Z, Zeng L, Hu J (2023) Microplastic pollution in the groundwater under a bedrock island in the South China sea. Environmental Research, 239, 117277.
DOI 10.1016/j.envres.2023.117277

Grechi N, Ferronato G, Devkota S, Ferraz MAMM (2024) Microplastics are detected in bull epididymal sperm and polystyrene microparticles impair sperm fertilization. Biology of Reproduction, 111(6), 1341–1351.
DOI 10.1093/biolre/ioae154

He W, Connolly ED, Wu G (2024) Characteristics of the Digestive Tract of Dogs and Cats. In G. Wu (Ed.), Nutrition and Metabolism of Dogs and Cats (Vol. 1446, pp. 15–38). Springer Nature Switzerland.
DOI 10.1007/978-3-031-54192-6_2

Hollóczki O, Gehrke S (2020) Can Nanoplastics Alter Cell Membranes? ChemPhysChem, 21(1), 9–12.
DOI 10.1002/cphc.201900481

Hornek-Gausterer R, Oberacher H, Reinstadler V, Hartmann C, Liebmann B, Lomako I, Scharf S, Posautz A, Kübber-Heiss A (2021) A preliminary study on the detection of potential contaminants in the European brown hare (Lepus europaeus) by suspect and microplastics screening. Environmental Advances, 4, 100045.
DOI 10.1016/j.envadv.2021.100045

Horton A A, Walton A, Spurgeon DJ, Lahive E, Svendsen C (2017) Microplastics in freshwater and terrestrial environments: Evaluating the current understanding to identify the knowledge gaps and future research priorities. Science of The Total Environment, 586, 127–141.
DOI 10.1016/j.scitotenv.2017.01.190

Horvatits T, Tamminga M, Liu B, Sebode M, Carambia A, Fischer L, Püschel K, Huber S, Fischer EK (2022) Microplastics detected in cirrhotic liver tissue. eBioMedicine, 82, 104147.
DOI 10.1016/j.ebiom.2022.104147

Hu CJ, Garcia MA, Nihart A, Liu R, Yin L, Adolphi N, Gallego DF, Kang H, Campen MJ, Yu X (2024) Microplastic presence in dog and human testis and its potential association with sperm count and weights of testis and epididymis. Toxicological Sciences, 200(2), 235–240.
DOI 10.1093/toxsci/kfae060

Huang, M., Si, C., Qiu, C., & Wang, G. (2024). Microplastics analysis: From qualitative to quantitative. Environmental Science: Advances, 3, 1652–1668.
DOI 10.1039/D4VA00244J

Huerta Lwanga E, Gertsen H, Gooren H, Peters P, Salánki T, Van Der Ploeg M, Besseling E, Koelmans AA, Geissen V (2016) Microplastics in the Terrestrial Ecosystem: Implications for Lumbricus terrestris (Oligochaeta, Lumbricidae). Environmental Science & Technology, 50(5), 2685–2691.
DOI 10.1021/acs.est.5b05478

Huerta Lwanga E, Mendoza Vega J, Ku Quej V, Chi J de los A, Sanchez del Cid L, Chi C, Escalona Segura G, Gertsen H, Salánki T, van der Ploeg M, Koelmans AA, Geissen V (2017) Field evidence for transfer of plastic debris along a terrestrial food chain. Scientific Reports, 7(1), 14071.
DOI 10.1038/s41598-017-14588-2

Ibrahim YS, Tuan Anuar S, Azmi AA, Wan Mohd Khalik WMA, Lehata S, Hamzah SR, Ismail D, Ma ZF, Dzulkarnaen A, Zakaria Z, Mustaffa N, Tuan Sharif SE, Lee YY (2020) Detection of microplastics in human colectomy specimens. JGH Open, 5(1), 116–121.
DOI 10.1002/jgh3.12457

Islam MS, Rahman MdM, Larpruenrudee P, Arsalanloo A, Beni HM, Islam MdA, Gu Y, Sauret E (2023) How microplastics are transported and deposited in realistic upper airways? Physics of Fluids, 35(6), 063319.
DOI 10.1063/5.0150703

Islam MS, Saha SC, Gemci T, Yang IA, Sauret E, Ristovski Z, Gu Y T (2019) Euler-Lagrange Prediction of Diesel-Exhaust Polydisperse Particle Transport and Deposition in Lung: Anatomy and Turbulence Effects. Scientific Reports, 9(1), 12423.
DOI 10.1038/s41598-019-48753-6

Jenner LC, Rotchell JM, Bennett RT, Cowen M, Tentzeris V, Sadofsky LR (2022) Detection of microplastics in human lung tissue using μFTIR spectroscopy. Science of The Total Environment, 831, 154907.
DOI 10.1016/j.scitotenv.2022.154907

Jeon M S, Kim JW, Han YB, Jeong MH, Kim HR, Sik Kim H, Park YJ. Chung KH (2023) Polystyrene microplastic particles induce autophagic cell death in BEAS-2B human bronchial epithelial cells. Environmental Toxicology, 38(2), 359–367.
DOI 10.1002/tox.23705

Kanteraki A, Isari EA, Svarnas P, Kalavrouziotis IK (2022) Biosolids: The Trojan horse or the beautiful Helen for soil fertilization? Science of The Total Environment, 839, 156270.
DOI 10.1016/j.scitotenv.2022.156270

Kopatz V, Wen K, Kovács T, Keimowitz AS, Pichler V, Widder J, Vethaak AD, Hollóczki O, Kenner L (2023) Micro- and Nanoplastics Breach the Blood–Brain Barrier (BBB): Biomolecular Corona’s Role Revealed. Nanomaterials, 13(8), 1404.
DOI 10.3390/nano13081404

La Porta E, Exacoustos O, Lugani F, Angeletti A, Chiarenza DS, Bigatti C, Spinelli S, Kajana , Garbarino A, Bruschi M, Candiano G, Caridi G, Mancianti N, Calatroni M, Verzola D, Esposito P, Viazzi F, Verrina E, Ghiggeri GM (2023) Microplastics and Kidneys: An Update on the Evidence for Deposition of Plastic Microparticles in Human Organs, Tissues and Fluids and Renal Toxicity Concern. International Journal of Molecular Sciences, 24(18), Article 18.
DOI 10.3390/ijms241814391

Leslie HA, van Velzen MJM, Brandsma SH, Vethaak AD, Garcia-Vallejo JJ, Lamoree MH (2022a) Discovery and quantification of plastic particle pollution in human blood. Environment International, 163, 107199.
DOI 10.1016/j.envint.2022.107199

Leslie HA, van Velzen MJM, Brandsma SH, Vethaak AD, Garcia-Vallejo JJ, Lamoree MH (2022b) Discovery and quantification of plastic particle pollution in human blood. Environment International, 163, 107199.
DOI 10.1016/j.envint.2022.107199

Li H, Yang Z, Jiang F, Li L, Li Y, Zhang M, Qi Z, Ma R, Zhang Y, Fang J, Chen X, Geng Y, Cao Z, Pan G, Yan L, Sun W (2023) Detection of microplastics in domestic and fetal pigs’ lung tissue in natural environment: A preliminary study. Environmental Research, 216, 114623.
DOI 10.1016/j.envres.2022.114623

Li J, Green C, Reynolds A, Shi H, Rotchell JM (2018) Microplastics in mussels sampled from coastal waters and supermarkets in the United Kingdom. Environmental Pollution, 241, 35–44.
DOI 10.1016/j.envpol.2018.05.038

Li L, Xu Y, Li S, Zhang X, Feng H, Dai Y, Zhao J, Yue T (2022) Molecular modeling of nanoplastic transformations in alveolar fluid and impacts on the lung surfactant film. Journal of Hazardous Materials, 427, 127872.
DOI 10.1016/j.jhazmat.2021.127872

Li N, Yang , Dong Y, Wei B, Liang L, Yun X, Tian J, Zheng Y, Duan S, Zhang L (2024) Prevalence and implications of microplastic contaminants in general human seminal fluid: A Raman spectroscopic study. Science of The Total Environment, 937, 173522.
DOI 10.1016/j.scitotenv.2024.173522

Li Y, Chen L, Zhou N, Chen , Ling, Z, Xiang P (2024) Microplastics in the human body: A comprehensive review of exposure, distribution, migration mechanisms, and toxicity. Science of The Total Environment, 946, 174215.
DOI 10.1016/j.scitotenv.2024.174215

Li Z, Zheng Y, Maimaiti Z, Fu J, Yang F, Li Z-Y, Shi Y, Hao L-B, Chen J-Y, Xu C (2024) Identification and analysis of microplastics in human lower limb joints. Journal of Hazardous Materials, 461, 132640.
DOI 10.1016/j.jhazmat.2023.132640

Liu , Wang, C, Yang Y, Du Z, Li L, Zhang M, Ni S, Yue Z, Yang K, Wang Y, Li X, Yan Y, Qin Y, Li J, Yang Y, Zhang M (2024) Microplastics in three types of human arteries detected by pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS). Journal of Hazardous Materials, 469, 133855.
DOI 10.1016/j.jhazmat.2024.133855

Liu S, Guo J, Liu X, Yang R, Wang H, Sun Y, Chen B, Dong R (2023) Detection of various microplastics in placentas, meconium, infant feces, breastmilk and infant formula: A pilot prospective study. Science of The Total Environment, 854, 158699.
DOI 10.1016/j.scitotenv.2022.158699

Mariano S, Tacconi S, Fidaleo M, Rossi M, Dini L (2021) Micro and Nanoplastics Identification: Classic Methods and Innovative Detection Techniques. Frontiers in Toxicology, 3.
DOI 10.3389/ftox.2021.636640

Massardo S, Verzola D, Alberti S, Caboni C, Santostefano M, Eugenio Verrina E, Angeletti A, Lugani F, Ghiggeri GM, Brusch M, Candiano G, Rume N, Gentile M, Cravedi P, La Maestra S, Zaza G, Stallone G, Esposito P, Viazzi F, Mancianti N,… Artini C (2024) MicroRaman spectroscopy detects the presence of microplastics in human urine and kidney tissue. Environment International, 184, 108444.
DOI 10.1016/j.envint.2024.108444

Meegoda JN, Hettiarachchi MC (2023) A Path to a Reduction in Micro and Nanoplastics Pollution. International Journal of Environmental Research and Public Health, 20(8), 5555.
DOI 10.3390/ijerph20085555

Meixner, K., Kubiczek, M., Fritz, I., & Institute of Environmental Biotechnology; Department of Agrobiotechnology, IFA-Tulln; University of Natural Resources and Life Sciences, Vienna; Konrad Lorenz Straße 20, 3430 Tulln, Austria. (2020). Microplastic in soil–current status in Europe with special focus on method tests with Austrian samples. AIMS Environmental Science, 7(2), 174–191.
DOI 10.3934/environsci.2020011

Mistr M., Sfriso AA, Casoni E, Nicoli M, Vaccaro C, Munari C (2022) Microplastic accumulation in commercial fish from the Adriatic Sea. Marine Pollution Bulletin, 174, 113279.
DOI 10.1016/j.marpolbul.2021.113279

Moreira-Mendieta A, Garcia-Garin O, Muñoz-Pérez JP, Urquía DO, Drago M, Borrell A, Páez-Rosas D (2023) Detection and quantification of microplastic pollution in the endangered Galapagos sea lion. Science of The Total Environment, 896, 166223.
DOI 10.1016/j.scitotenv.2023.166223

Nessi A, Winkler A, Tremolada P, Saliu F, Lasagni M, Ghezzi LLM, Balestrieri, A (2022) Microplastic contamination in terrestrial ecosystems: A study using barn owl (Tyto alba) pellets. Chemosphere, 308, 136281.
DOI 10.1016/j.chemosphere.2022.136281

Öling-Wärnå V, Åkerback N,Engblom, S (2023) Digestate from Biowaste and Sewage Sludge as Carriers of Microplastic into the Environment: Case Study of a Thermophilic Biogas Plant in Ostrobothnia, Finland. Water, Air, & Soil Pollution, 234(7), 432.
DOI 10.1007/s11270-023-06436-z

Oliveri Conti G, Ferrante M, Banni M, Favara C, Nicolosi I, Cristaldi A, Fiore M, Zuccarello P (2020) Micro- and nano-plastics in edible fruit and vegetables. The first diet risks assessment for the general population. Environmental Research, 187, 109677.
DOI 10.1016/j.envres.2020.109677

Ośko, J., Jażdżewska, K., Nowak, N., Kowalczyk, P., & Grembecka, M. (2025). Nanoplastics: From Separations to Analysis—Challenges and Limitations. Separations, 12(7), 185.
DOI 10.3390/separations12070185

Peng M, Vercauteren M, Grootaert C, Rajkovic A, Boon N, Janssen C, Asselman J (2023) Cellular and bioenergetic effects of polystyrene microplastic in function of cell type, differentiation status and post-exposure time. Environmental Pollution, 337, 122550.
DOI 10.1016/j.envpol.2023.122550

Periyasamy AP, Tehrani-Bagha A (2022) A review on microplastic emission from textile materials and its reduction techniques. Polymer Degradation and Stability, 199, 109901.
DOI 10.1016/j.polymdegradstab.2022.109901

Poli V, Litti L, Lavagnolo MC (2024). Microplastic Pollution in The North-East Atlantic Ocean Surface Water: How the Sampling Approach Influences the Extent of the Issue. STOTEN.
DOI 10.1016/j.scitotenv.2024.174561

Porterfield KK, Hobson SA, Neher DA, Niles MT, Roy ED (2023) Microplastics in composts, digestates, and food wastes: A review. Journal of Environmental Quality, 52(2), 225–240.
DOI 10.1002/jeq2.20450

Porterfield, K. K., Hobson, S. A., Neher, D. A., Niles, M. T., & Roy, E. D. (2023). Microplastics in composts, digestates, and food wastes: A review. Journal of Environmental Quality, 52(2), 225–240.
DOI 10.1002/jeq2.20450

Prata J C, Silva ALP, da Costa JP, Dias-Pereira P, Carvalho A, Fernandes AJS, da Costa F, Duarte AC, Rocha-Santos, T (2022) Microplastics in Internal Tissues of Companion Animals from Urban Environments. Animals, 12(15), Article 15.
DOI 10.3390/ani12151979

Prata, J. C. (2018). Airborne microplastics: Consequences to human health? Environmental Pollution, 234, 115–126.
DOI 10.1016/j.envpol.2017.11.043

Quartinello F, Kremser K, Schoen H, Tesei D, Ploszczanski , Nagle M, Podmirseg SM, Insam H, Piñar G, Sterflingler K, Ribitsch D, Guebitz GM (2021) Together Is Better: The Rumen Microbial Community as Biological Toolbox for Degradation of Synthetic Polyesters. Frontiers in Bioengineering and Biotechnology, 9, 684459.
DOI 10.3389/fbioe.2021.684459

Ragusa A, Matta M, Cristiano L, Matassa R, Battaglione E, Svelato A, De Luca C, D’Avino S, Gulotta A, Rongioletti MCA, Catalano P, Santacroce C, Notarstefano V, Carnevali O, Giorgini E, Vizza E, Familiari G, Nottola SA (2022) Deeply in Plasticenta: Presence of Microplastics in the Intracellular Compartment of Human Placentas. International Journal of Environmental Research and Public Health, 19(18), Article 18.
DOI 10.3390/ijerph191811593

Ragusa A, Svelato A, Santacroce C, Catalano P, Notarstefano V, Carnevali O, Papa,F, Rongioletti MCA, Baiocco F, Draghi S, D’Amore E, Rinaldo D, Matta M, Giorgini E(2021) Plasticenta: First evidence of microplastics in human placenta. Environment International, 146, 106274.
DOI 10.1016/j.envint.2020.106274

Rajendran D, Chandrasekaran N (2023) Journey of micronanoplastics with blood components. RSC Advances, 13(45), 31435–31459.
DOI 10.1039/D3RA05620A

Rossi G, Barnoud J, Monticell L. (2014) Polystyrene Nanoparticles Perturb Lipid Membranes. The Journal of Physical Chemistry Letters, 5(1), 241–246.
DOI 10.1021/jz402234c

Rotchell JM, Jenner LC, Chapman E, Bennett RT, Bolanle IO, Loubani M, Sadofsky L, Palme TM (2023) Detection of microplastics in human saphenous vein tissue using μFTIR: A pilot study. PLOS ONE, 18(2), e0280594.
DOI 10.1371/journal.pone.0280594

Saha SC, Saha (2024). Effect of microplastics deposition on human lung airways: A review with computational benefits and challenges. Heliyon, 10(2), e24355.
DOI 10.1016/j.heliyon.2024.e24355

Shao, K., Zou, R., Zhang, Z., Mandemaker, L. D. B., Timbie, S., Smith, R. D., Durkin, A. M., Dusza, H. M., Meirer, F., Weckhuysen, B. M., Alderete, T. L., Vermeulen, R., & Walker, D. I. (2025). Advancements in assays for micro- and nanoplastic detection: Paving the way for biomonitoring and exposomics studies. Annual Review of Pharmacology and Toxicology, 65(1), 567-585.
DOI 10.1146/annurev-pharmtox-030424-112828

Shim WJ, Hong SH, Eo SE (2017) Identification methods in microplastic analysis: A review. Analytical Methods, 9(9), 1384–1391.
DOI 10.1039/C6AY02558G

Srivastava P, Saji J, Manickam N (2024) Biodegradation of polyethylene terephthalate (PET) by Brucella intermedia IITR130 and its proposed metabolic pathway. Biodegradation 35, 671–685
DOI 10.1007/s10532-024-10070-9

Stock, F. et al., (2020). Pitfalls and Limitations in Microplastic Analyses. In: Stock, F., Reifferscheid, G., Brennholt, N., Kostianaia, E. (eds) Plastics in the Aquatic Environment - Part I. The Handbook of Environmental Chemistry, vol 111. Springer, Cham.
DOI 10.1007/698_2020_654

Truong T-N-S, Strady , Kieu-Le, T-C, Tran Q-V, Le T-M-T Thuong Q-T (2021) Microplastic in atmospheric fallouts of a developing Southeast Asian megacity under tropical climate. Chemosphere, 272, 129874.
DOI 10.1016/j.chemosphere.2021.129874

VL Leonard S, Liddle CR. Atherall CA, Chapman E, Watkins MDJ, Calaminus S, Rotchell JM (2024) Microplastics in human blood: Polymer types, concentrations and characterisation using μFTIR. Environment International, 188, 108751.
DOI 10.1016/j.envint.2024.108751

Wang T, Yi Z, Liu X, Cai Y, Huang X Fang J, Shen R, Lu W. Xiao Y, Zhuan W, Gu S. (2024) Multimodal detection and analysis of microplastics in human thrombi from multiple anatomically distinct sites. eBioMedicine, 103, 105118.
DOI 10.1016/j.ebiom.2024.105118

Wang W, Zhang J, Qiu Z, Cui Z, Li N, Li X, Wang Y, Zhang H, Zhao C (2022) Effects of polyethylene microplastics on cell membranes: A combined study of experiments and molecular dynamics simulations. Journal of Hazardous Materials, 429, 128323.
DOI 10.1016/j.jhazmat.2022.128323

Weingrill RB, Lee M-J, Benny P, Riel J, Saiki K, Garcia J, Oliveira LFA de M, Fonseca EJ da S, Souza ST de, D’Amato F de OS, Silva UR., Dutra ML, Marques ALX, Borbely AU, Urschitz J (2023) Temporal trends in microplastic accumulation in placentas from pregnancies in Hawaiʻi. Environment International, 180, 108220.
DOI 10.1016/j.envint.2023.108220

Wu D, Feng Y, Wang R, Jiang J, Guan Q, Yang X, Wei H, Xia Y, Luo Y (2023) Pigment microparticles and microplastics found in human thrombi based on Raman spectral evidence. Journal of Advanced Research, 49, 141–150.
DOI 10.1016/j.jare.2022.09.004

Yan Z, Liu Y, Zhang T, Zhang F, Ren H, Zhang Y (2022) Analysis of Microplastics in Human Feces Reveals a Correlation between Fecal Microplastics and Inflammatory Bowel Disease Status. Environmental Science & Technology, 56(1), 414–421.
DOI 10.1021/acs.est.1c03924

Yang W, Wu L, Li G, Shi L, Zhang J, Liu L, Chen Y, Yu H, Wang K, Xin L, Tang D, Shen Q, Xu C, Geng H, Wu H, Duan Z, Cao Y, He X (2024) Atlas and source of the microplastics of male reproductive system in human and mice. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH.
DOI 10.1007/s11356-024-32832-x

Yang Z, Wang M, Feng Z, Wang Z, Lv M, Chang J, Chen L, Wang C (2023) Human Microplastics Exposure and Potential Health Risks to Target Organs by Different Routes: A Review. Current Pollution Reports, 9(3), 468–485.
DOI 10.1007/s40726-023-00273-8

Yin X, Wu J, Liu Y, Chen X, Xie C, Liang Y, Li J, Jiang Z (2022) Accumulation of microplastics in fish guts and gills from a large natural lake: Selective or non-selective? Environmental Pollution, 309, 119785.
DOI 10.1016/j.envpol.2022.119785

Zha Q, Zhu L, Weng J, Jin Z, Cao Y, Jiang H, Zhang Z (2023) Detection and characterization of microplastics in the human testis and semen. Science of The Total Environment, 877, 162713.
DOI 10.1016/j.scitotenv.2023.162713

Zhang D, Wu C, Liu Y, Li W, Li S, Peng L, Kang L, Ullah S, Gong Z, Li Z, Ding D, Jin Z,Huang, H (2024) Microplastics are detected in human gallstones and have the ability to form large cholesterol-microplastic heteroaggregates. Journal of Hazardous Materials, 467, 133631.
DOI 10.1016/j.jhazmat.2024.133631

Zhu L, Kang Y, Ma M, Wu Z, Zhang L, Hu R, Xu Q, Zhu J, Gu X, An L (2024) Tissue accumulation of microplastics and potential health risks in human. Science of The Total Environment, 915, 170004.
DOI 10.1016/j.scitotenv.2024.170004

Zhu L, Zhu J, Zuo R, Xu Q, Qian Y, AnL (2023) Identification of microplastics in human placenta using laser direct infrared spectroscopy. Science of The Total Environment, 856, 159060.
DOI 10.1016/j.scitotenv.2022.159060

Zingaro F, Gianoncelli A, Ceccone G, Birarda G, Cassano D, La Spina R, Agostinis C, Bonanni V, Ricci G, Pascolo L (2023) Morphological and lipid metabolism alterations in macrophages exposed to model environmental nanoplastics traced by high-resolution synchrotron techniques. Frontiers in Immunology, 14.
DOI 10.3389/fimmu.2023.1247747

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